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CMS finalizes lower Medicare outpatient pay for 340B drugs at hospitals

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On November 6, 2026, CMS published its final 2027 hospital outpatient rule, which pays the average sales price minus 28 percent for 340B drugs from January 1, 2027. Rural sole community, children’s and cancer hospitals are excepted.

The 340B remedy offset on other services rises from 0.5 to 2 percent. No health center is named in the 340B policy.

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Cite this analysis

FQHC Talent. (2026, November 6). CMS finalizes lower Medicare outpatient pay for 340B drugs at hospitals. Source: Centers for Medicare & Medicaid Services — CY 2027 OPPS/ASC final rule with comment period CMS-1850-FC (Federal Register document 2026-22739, 91 FR 70284). Retrieved November 11, 2026, from https://www.fqhctalent.com/intel/cms-cy2027-opps-final-rule-340b-drugs-asp-minus-28-november-2026